What Is Alignment Phase I and Alignment Phase II in CBME?
- edicineindia
- May 15
- 3 min read
Have you ever wondered why medical students now learn Anatomy alongside Physiology and Biochemistry with clinical cases tied in from day one? Or why Pharmacology, Pathology, and Microbiology seem to connect like puzzle pieces? Well, welcome to the world of integration and it all starts with Alignment Phase I and Alignment Phase II in CBME.
In this blog, we’ll explore how these alignment phases are implemented under India’s CBME curriculum, what subjects are grouped, how they complement each other, and why this method matters more than you think. If you're a medical student or university faculty trying to understand CBME's integrated approach, this post is your roadmap.

The Concept of Alignment in CBME
In traditional systems, subjects were taught in silos. Anatomy in one classroom, Physiology in another, and Biochemistry somewhere else. CBME changes that. Alignment refers to teaching related topics across subjects at the same time, so they make better sense together.
Think of it as horizontal integration connecting subjects within the same phase to deepen understanding.
Phase I Alignment: Learning the Human Body as One System
Phase I (13 months) includes three core subjects:
Anatomy
Physiology
Biochemistry
Instead of teaching them separately, CBME aligns their topics. For example:
While studying the cardiovascular system in Anatomy (heart structure), you also study cardiac cycle in Physiology and enzymes like CK-MB in Biochemistry.
When learning about the liver’s histology, you also understand liver function tests and bile metabolism.
Benefits:
Helps you form complete concepts
Reinforces learning through repetition in different contexts
Prepares you for clinical application early
Alignment Phase I is supported with:
Early Clinical Exposure (ECE): Hospital or virtual visits during system-based learning
Small Group Teaching: Interactive discussions, not just lectures
Integrated Logbooks: Competency tracking across subjects
Phase II Alignment: Diseases and Defense Come Together
Phase II (11 months) includes:
Pathology
Pharmacology
Microbiology
Forensic Medicine
Community Medicine (continued)
Here, alignment takes a slightly clinical turn. For instance:
Studying tuberculosis in Microbiology? You’ll also learn its pathogenesis in Pathology and the treatment regimen in Pharmacology.
Discussing poisoning in Forensic Medicine? Pharmacology gives you the antidotes.
Integration Examples:
HIV/AIDS: virology (Micro), immunopathogenesis (Path), ART (Pharma)
Anemia: causes (Path), iron studies (Micro), supplements (Pharma)
Supported by:
Case-Based Discussions: Linking lab findings to treatment
Clinical Skill Demonstrations: Peripheral smear, drug administration
AETCOM Modules: Ethical dilemmas, breaking bad news
Why Alignment Matters for Medical Students
It’s one thing to memorize symptoms. It’s another to understand why they happen, how to investigate them, and what to prescribe. Alignment helps students:
See the bigger picture
Think like clinicians from early on
Reduce cognitive load by learning connected topics together
Perform better in integrated exams and eventually in NExT
Challenges in Implementation
Of course, aligning isn’t always easy. It needs:
Close coordination among departments
Timetable syncing
Joint assessment planning
Some colleges still struggle to align perfectly, but most have shown progress year by year.
So, what is Alignment Phase I and Alignment Phase II in CBME? It's not just about coordination it's about making learning meaningful. By linking subjects horizontally, CBME gives students a more complete, less fragmented view of medicine.
From day one, you're not just studying topics. You're understanding systems. And that makes all the difference when you finally meet your first patient.
For more guides on CBME, MBBS structure, and integration strategies, explore www.edicine.tech.
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